BackBiome: Probiotic Supplement Shows Promise for Gut-Spine Wellness Support

GlobeNewswire | BackBiome
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New York City, NY, Dec. 04, 2025 (GLOBE NEWSWIRE) --  BackBiome's development reflects recent scientific research illuminating an important connection between gut health and spinal comfort, with studies suggesting that digestive inflammation may influence discomfort in the back and spine. Research published in medical journals has investigated this relationship, finding evidence supporting a direct association between gastrointestinal inflammation and back discomfort.

This emerging field of research, known as the gut-spine axis, suggests that the proximity of the digestive system to the spinal column creates potential for inflammatory processes in the gut to affect spinal tissues. When the intestinal lining becomes compromised, a condition often referred to as increased intestinal permeability, inflammatory compounds may enter systemic circulation and potentially affect surrounding structures including the spine.

BackBiome has been expertly formulated based on the emerging scientific understanding of the gut-spine connection, combining seven carefully researched probiotic strains with a specialized honey delivery matrix designed to support digestive health and naturally help reduce discomfort through gut microbiome optimization. Growing research suggests that maintaining a healthy balance of beneficial bacteria in the digestive system may play a significant role in supporting overall comfort, wellbeing, and how our bodies respond to inflammation. To explore the complete science behind BackBiome's formulation, read verified user experiences, and discover exclusive offers, visit the official BackBiome website by clicking here. You'll find comprehensive resources to help you make an informed decision about your wellness journey.

Scientific literature increasingly supports the role of the gut microbiome in systemic inflammation regulation. Studies published in leading journals including Nature and PubMed have documented how specific probiotic strains may help modulate inflammatory responses and support digestive barrier function. This research provides the scientific foundation for BackBiome's formulation approach.

Additional research from Frontiers in Microbiology in 2024 established causal relationships between gut microbiota composition and spinal pain, further validating the gut-spine axis concept [5]. These findings suggest that addressing gut health through targeted probiotic supplementation may represent a novel approach to supporting spinal comfort and overall wellness.

The growing body of evidence supporting gut-spine connections has attracted attention from healthcare professionals and researchers worldwide. As reported by Medscape in 2025, new data continues to add to the understanding of how gut microbiome changes may influence chronic pain syndromes [4], providing additional scientific context for BackBiome's targeted approach to digestive and spinal wellness support.

BackBiome Probiotic Formula: Seven Researched Strains in Honey Matrix

BackBiome represents a carefully formulated probiotic supplement that combines seven extensively researched bacterial strains with a unique honey delivery matrix. This formulation approach is designed to support digestive health while potentially addressing spinal discomfort through the emerging science of the gut-spine axis. Each component of BackBiome has been selected based on published research demonstrating potential benefits for digestive wellness and inflammation modulation.

The BackBiome formula includes Bacillus subtilis as its primary strain, supported by multiple Lactobacillus species including acidophilus, plantarum, rhamnosus, and casei, along with Bifidobacterium longum and breve. This diverse combination of probiotic strains is designed to support various aspects of digestive function and may help maintain healthy inflammatory responses throughout the body.

The honey matrix delivery system serves multiple functions within the BackBiome formulation. Research suggests that honey's natural enzymes and prebiotic properties may help protect probiotic bacteria during digestion while providing nourishment for beneficial microorganisms. This delivery approach draws inspiration from traditional usage patterns, particularly the historical use of honey-based preparations by Australian Aboriginal populations for digestive wellness support.

BackBiome is manufactured in FDA-registered, GMP-certified facilities to ensure quality and consistency. Each batch undergoes third-party testing for potency and purity, providing consumers with confidence in the product's safety and effectiveness. The supplement is designed for daily use as part of a comprehensive approach to digestive and spinal wellness support.

Consumer satisfaction surveys reveal impressive positive outcomes among BackBiome users, with verified customer feedback demonstrating the supplement's potential effectiveness. According to comprehensive internal consumer surveys, 86% of verified BackBiome users report experiencing reduced morning stiffness, while an remarkable 90% express overall satisfaction with their BackBiome experience and results. These compelling findings suggest that the unique combination of researched probiotic strains with the specialized honey delivery system may provide meaningful, real-world benefits for individuals seeking natural digestive and spinal wellness support. To read detailed customer testimonials, explore the complete survey results, understand what users are saying about their personal experiences, and see before-and-after stories from verified customers, visit the official BackBiome website by clicking here. You can access authentic reviews and discover if this supplement aligns with your health goals.

BackBiome's Primary Ingredient: Bacillus Subtilis for Digestive Comfort


Bacillus subtilis serves as the cornerstone strain in the BackBiome formulation, supported by extensive published research demonstrating its potential benefits for digestive health and inflammation modulation. This spore-forming probiotic, sometimes referred to as the "honeybee probiotic" due to its natural presence in bee digestive systems, has been the subject of numerous clinical studies investigating its therapeutic potential.

A significant study published in PMC/NIH in 2022 demonstrated that Bacillus subtilis supplementation resulted in clinically significant reductions in gastrointestinal symptoms [2]. This research provides evidence for the strain's ability to support digestive comfort, which may be particularly relevant for individuals experiencing gut-related discomfort that could potentially affect spinal wellness through the gut-spine axis.

Research literature supports Bacillus subtilis' anti-inflammatory potential, with multiple studies demonstrating that this strain exhibits beneficial properties for inflammation modulation. These findings support BackBiome's inclusion of this strain for wellness purposes.

Perhaps most relevant to BackBiome's targeted approach is a 2015 study published in PMC/NIH that investigated Bacillus subtilis var. natto supplementation in relation to circulation-related symptoms. This research found that participants experienced improvements in symptoms including lower back pain relief[3]. This study provides evidence supporting the potential of Bacillus subtilis for comfort applications. Visit official website here, and explore the complete BackBiome formula.

The mechanisms by which Bacillus subtilis may support digestive and spinal wellness appear to involve multiple pathways. Research suggests the strain may help strengthen intestinal barrier function, reduce inflammatory cytokine production, and support healthy immune responses. These effects may contribute to reduced systemic inflammation that could potentially benefit spinal tissues and surrounding structures.

Traditional knowledge systems have long recognized the potential benefits of Bacillus subtilis-containing preparations. Historical use by various cultures, particularly in fermented foods and traditional medicine systems, provides additional context for the strain's safety profile and potential therapeutic applications. This combination of traditional use and modern scientific validation supports Bacillus subtilis' inclusion as BackBiome's primary active ingredient.

BackBiome Supporting Strains: Lactobacillus and Bifidobacterium Species

The BackBiome formulation extends beyond Bacillus subtilis to include carefully selected Lactobacillus and Bifidobacterium species, each supported by published research demonstrating specific benefits for digestive health and inflammation modulation. This multi-strain approach is designed to provide comprehensive support for gut microbiome balance and may help address various aspects of the gut-spine wellness connection.

Lactobacillus acidophilus, included in the BackBiome formula, has been extensively studied for its anti-nociceptive properties, meaning it has a potential to help reduce pain sensitivity. Published research suggests that this strain may help boost the expression of natural pain-relieving compounds in the body, creating effects that support comfort and wellbeing. Additionally, Lactobacillus acidophilus has been shown to help reverse gut dysbiosis and restore healthy intestinal microflora balance.

Lactobacillus plantarum, another key component of BackBiome, has demonstrated significant potential for reducing inflammatory cytokines and molecules throughout the body. Research indicates that this strain may help modulate immune responses and support healthy inflammatory processes, which could be particularly beneficial for addressing systemic inflammation that may affect spinal tissues through the gut-spine axis.

The inclusion of Lactobacillus rhamnosus in BackBiome is supported by studies showing its ability to reduce intestinal inflammation while simultaneously restoring the protective mucous layer of the gut. This dual action may help minimize inflammation in the spine and surrounding tissues, which is why researchers have referred to this strain as a promising anti-inflammatory agent for systemic wellness applications.

Lactobacillus casei rounds out the Lactobacillus species in BackBiome, with clinical research demonstrating its potential for pain management applications. Studies have found that Lactobacillus casei supplementation may help reduce inflammatory cytokines while supporting healthy gut function and potentially reducing spinal inflammation. This strain has also been associated with mood support and chronic fatigue management, providing additional wellness benefits.

The Bifidobacterium species included in BackBiome provide additional support for long-term gut health maintenance. Bifidobacterium longum has been shown to help stabilize gut microbiota and maintain normal intestinal barrier function while supporting healthy inflammatory responses. Meanwhile, Bifidobacterium breve has demonstrated potential for inflammation regulation and may support healthy weight management, providing comprehensive wellness benefits beyond digestive health.

The synergistic combination of these probiotic strains in BackBiome is designed to address multiple aspects of gut-spine wellness simultaneously. Research suggests that multi-strain probiotic formulations may provide more comprehensive benefits than single-strain supplements, supporting the rationale for BackBiome's diverse bacterial profile. Each strain contributes unique mechanisms of action that may collectively support digestive health, inflammation modulation, and spinal comfort through the emerging gut-spine axis.

BackBiome Honey Matrix Delivery System: Traditional Wisdom Meets Science

The honey matrix delivery system employed in BackBiome represents a sophisticated approach to probiotic supplementation that combines traditional knowledge with modern scientific understanding. This delivery method serves multiple functions, acting simultaneously as a protective medium for probiotic bacteria, a prebiotic substrate to nourish beneficial microorganisms, and a source of bioactive compounds that may support overall wellness.

Research suggests that honey's natural enzyme content and antimicrobial properties create an ideal environment for maintaining probiotic viability during storage and digestion. The honey matrix may help protect sensitive bacterial strains from gastric acid and bile salts, potentially increasing the number of viable organisms that reach the intestinal tract where they can provide therapeutic benefits.

The prebiotic function of honey within the BackBiome formulation provides nourishment for both supplemented probiotic strains and existing beneficial bacteria in the gut microbiome. Honey contains naturally occurring oligosaccharides and other complex carbohydrates that serve as preferred fuel sources for beneficial bacteria, potentially enhancing their growth and metabolic activity within the digestive system.

Traditional knowledge systems provide historical context for honey-based therapeutic preparations. Australian Aboriginal cultures have traditionally used honey-containing preparations for digestive wellness support, demonstrating long-term human experience with honey as a delivery medium for therapeutic compounds. This traditional usage provides additional confidence in the safety and potential efficacy of honey-based supplement formulations.

The bioactive compounds naturally present in honey may provide additional wellness benefits beyond probiotic delivery. Research indicates that honey contains antioxidants, anti-inflammatory compounds, and other bioactive substances that may support immune function, reduce oxidative stress, and promote overall health. These properties complement the probiotic strains in BackBiome to provide comprehensive wellness support.

BackBiome Consumer Satisfaction: 90% Report Positive Outcomes

Consumer satisfaction surveys and user experience data provide valuable real-world evidence supporting the effectiveness of BackBiome supplementation. According to internal consumer surveys, individuals who consistently use BackBiome report meaningful improvements in multiple aspects of digestive and spinal wellness, with satisfaction rates indicating that the supplement meets or exceeds user expectations in most cases.

Survey data indicates that 86% of verified BackBiome users report experiencing reduced morning stiffness after incorporating the supplement into their daily wellness routines. This finding is particularly significant given that morning stiffness often represents one of the most challenging aspects of spinal discomfort for many individuals. The high percentage of users reporting improvement suggests that BackBiome's gut-spine approach may provide meaningful benefits for this common concern.

Movement and mobility improvements represent another significant area of user-reported benefits. According to internal consumer surveys, 79% of BackBiome users report easier movement transitions, including activities such as bending, standing, and sitting. These functional improvements may contribute to enhanced quality of life and increased participation in daily activities for users seeking spinal wellness support. Visit the official BackBiome site for verified ingredients and exclusive offers.

Digestive wellness improvements are reported by 83% of BackBiome users, with individuals noting improved digestion and enhanced post-meal comfort. These findings support the supplement's primary function as a probiotic formulation while also suggesting that improved gut health may contribute to overall wellness benefits that extend beyond digestive function alone.

Energy and alertness improvements are noted by 74% of BackBiome users, who report experiencing noticeable boosts in daily energy levels and enhanced mental alertness. These benefits may result from improved nutrient absorption, reduced inflammatory burden, or enhanced overall wellness resulting from gut microbiome optimization. The connection between gut health and energy levels is supported by growing research in the gut-brain axis field.

Overall satisfaction with BackBiome reaches 90% among verified users, indicating that the vast majority of individuals who try the supplement find it helpful for their wellness goals. This high satisfaction rate suggests that BackBiome delivers on its promises and provides meaningful benefits for users seeking digestive and spinal wellness support through probiotic supplementation.

How BackBiome Targets the Gut-Spine Connection

The relationship between gut health and spinal comfort involves complex biological mechanisms that researchers are continuing to investigate and understand. Current scientific evidence suggests that the digestive system and spinal structures may be connected through multiple pathways, including inflammatory signaling, anatomical proximity, and shared neural networks that could potentially influence comfort and discomfort in both systems.

One proposed mechanism involves the concept of increased intestinal permeability, commonly referred to as "leaky gut syndrome." When the intestinal barrier becomes compromised, potentially harmful substances that normally remain within the digestive tract may enter systemic circulation. These substances can trigger inflammatory responses throughout the body, potentially affecting tissues and structures distant from the original source, including spinal tissues and surrounding muscles.

The anatomical proximity of the digestive organs to the spinal column provides another potential pathway for gut-spine interactions. Research suggests that inflammation within the digestive system may cause intestinal expansion that could potentially affect spinal alignment or place pressure on surrounding tissues. This physical relationship may explain why some individuals experience changes in back comfort corresponding to digestive symptoms or meal consumption.

Inflammatory cytokines and signaling molecules produced in response to gut dysbiosis may circulate throughout the body and potentially affect spinal tissues, nerves, and supporting structures. Research indicates that chronic low-grade inflammation originating in the gut may contribute to systemic inflammatory processes that could influence comfort levels in various body regions, including the back and spine.

The vagus nerve, which connects the brain to various organs including the digestive system, may also play a role in gut-spine communication. This critical neural pathway influences inflammation regulation, immune function, and pain perception throughout the body. Disruptions in vagal function due to gut health issues could potentially affect the body's ability to regulate inflammatory responses in spinal tissues.

Nutrient absorption and metabolic factors represent additional mechanisms by which gut health may influence spinal wellness. Compromised digestive function may lead to reduced absorption of nutrients critical for bone health, muscle function, and tissue repair, potentially affecting the structural integrity and comfort of spinal tissues over time. Supporting optimal gut health through targeted probiotic supplementation may help ensure adequate nutrient availability for spinal tissue maintenance and repair.

Using BackBiome: Daily Supplementation for Optimal Results

BackBiome is designed for convenient daily use as part of a comprehensive approach to digestive and spinal wellness support. The supplement is typically taken as directed on the product packaging, with most users incorporating it into their morning routine for optimal consistency and convenience. The honey-based formula is generally well-tolerated and can be taken with or without food according to individual preferences.

New BackBiome users should understand that probiotic supplements typically require a period of adaptation as beneficial bacteria establish themselves within the gut microbiome. Research suggests that meaningful changes in gut microbial composition may take 2-8 weeks of consistent use, with some individuals experiencing benefits sooner while others may require longer periods to notice significant changes.

During the initial weeks of BackBiome supplementation, some users may experience mild digestive changes as their gut microbiome adapts to the introduction of new bacterial strains. These changes, which may include temporary alterations in bowel movements or mild bloating, are generally considered normal and typically resolve as the microbiome reaches a new equilibrium state.

Many BackBiome users report that digestive improvements are among the first benefits they notice, often within the first few weeks of consistent use. These may include reduced bloating, improved regularity, enhanced comfort after meals, and general improvements in digestive function. These early digestive benefits may serve as indicators that the probiotic strains are establishing themselves successfully.

Spinal comfort improvements, when experienced, typically develop more gradually as systemic inflammation modulation and gut barrier function improvements take effect. Users report varying timeframes for noticing spinal wellness benefits, with some experiencing changes within 3-4 weeks while others may require 6-8 weeks of consistent use to notice meaningful improvements in comfort and mobility.

For optimal results, healthcare professionals generally recommend maintaining consistent daily use of probiotic supplements rather than intermittent or irregular supplementation. The beneficial effects of probiotic supplementation are typically maintained only as long as supplementation continues, making consistency an important factor in achieving and maintaining desired outcomes with BackBiome.

BackBiome Manufacturing: GMP-Certified Facilities Ensure Quality

BackBiome is manufactured according to stringent quality standards designed to ensure product safety, consistency, and effectiveness. The supplement is produced in facilities certified under Good Manufacturing Practices (GMP) guidelines, providing consumers with confidence in the product's quality and safety profile.

Each batch of BackBiome undergoes comprehensive third-party testing to verify potency, purity, and safety. These testing protocols include verification of probiotic strain identity and viability, screening for contaminants such as heavy metals and harmful microorganisms, and confirmation that the product meets specified potency levels for each included bacterial strain.

The honey used in BackBiome's delivery matrix is sourced from suppliers who meet strict quality standards for purity and processing. The honey undergoes testing to ensure it is free from adulterants, pesticides, and other potentially harmful substances while retaining its beneficial enzymatic and prebiotic properties. This careful sourcing helps ensure that the honey matrix provides optimal support for probiotic viability and effectiveness.

Storage and handling protocols for BackBiome are designed to maintain probiotic viability throughout the product's shelf life. The supplement is packaged in protective containers that shield sensitive bacterial strains from light, moisture, and temperature fluctuations that could compromise their effectiveness. Proper storage instructions are provided to help consumers maintain product quality after purchase.

Quality assurance measures include batch tracking systems that allow for complete traceability from raw materials through final packaging. This comprehensive tracking system enables rapid response to any quality concerns and provides consumers with additional confidence in the product's safety and consistency. Manufacturing records are maintained according to industry standards for supplement production facilities.

BackBiome Pricing

BackBiome is available in multiple package options designed to accommodate different needs, budgets, and commitment levels for digestive and spinal wellness support. Each package includes the same high-quality honey-based probiotic formulation, with larger packages offering enhanced value for users committed to long-term supplementation and wellness optimization.

BackBiome Single Bottle Package

  • Price: $69 (Regular price: $197 - Save $128)
  • Supply: One 30-day supply of BackBiome honey-based probiotic formula
  • Formula: Seven researched probiotic strains including Bacillus subtilis
  • Delivery System: Honey matrix delivery system for enhanced probiotic viability
  • Includes: Comprehensive usage instructions and wellness guidance
  • Guarantee: 60-day money-back satisfaction guarantee

The single bottle option provides an excellent introduction to BackBiome for individuals who want to experience the potential benefits of the honey-based probiotic formula before committing to larger quantities. This package allows users to evaluate their individual response to the supplement while taking advantage of significant savings compared to the regular retail price. Visit the Official Website to secure your order today.

BackBiome Three-Bottle Package

  • Price: Contact for current pricing (Additional savings on 3-month supply)
  • Supply: Three bottles providing 90 days of BackBiome supplementation
  • Value: Enhanced pricing for extended use commitment
  • Benefits: Sufficient supply to experience full probiotic adaptation benefits
  • Shipping: Free shipping on three-bottle orders
  • Guarantee: 60-day money-back satisfaction guarantee

The three-bottle package recognizes that optimal probiotic benefits often develop over 2-3 months of consistent use. This option provides users with sufficient supply to experience the full range of potential benefits while offering enhanced value compared to single bottle purchases. Many users find that three months of consistent supplementation allows for optimal gut microbiome adaptation.

BackBiome Six-Bottle Package

  • Price: $49 per bottle (Regular price: $197 per bottle - Save $888 total)
  • Supply: Six bottles providing 180 days of comprehensive probiotic support
  • Value: Maximum per-bottle savings for committed users
  • Duration: Extended supply for long-term wellness optimization
  • Shipping: Priority shipping and handling
  • Guarantee: 60-day money-back satisfaction guarantee
  • Bonus: Wellness resources and optimization guides included

The six-bottle package provides exceptional value for users committed to long-term digestive and spinal wellness support through consistent probiotic supplementation. This comprehensive option offers the lowest per-bottle pricing available, ensuring uninterrupted daily supplementation for six months and allowing your body adequate time to experience the full potential of BackBiome's innovative gut-spine axis approach to wellness optimization. By choosing the six-bottle package, you're investing in sustained microbiome balance that research suggests may take several months to fully establish and deliver optimal comfort benefits. To explore all available package options, compare pricing details, see current promotional discounts, and secure the best value for your wellness investment with exclusive bundle savings, visit the official BackBiome website by clicking here. You'll find detailed package breakdowns and limited-time offers designed to make long-term wellness support more affordable.

All BackBiome packages are backed by a comprehensive 60-day money-back satisfaction guarantee, allowing users to try the supplement with confidence. This guarantee reflects the company's confidence in BackBiome's potential benefits and provides consumers with risk-free opportunity to experience the supplement's effects on their digestive and spinal wellness goals.

BackBiome's Approach: Understanding Probiotic Wellness

Probiotic supplementation represents a scientifically-supported approach to wellness that focuses on optimizing the gut microbiome to support overall health and wellbeing. The human digestive system contains trillions of microorganisms that play crucial roles in digestion, immune function, inflammation regulation, and various other physiological processes that extend far beyond the gut itself.

Research has demonstrated that the composition and balance of gut bacteria can significantly influence systemic health outcomes, including inflammatory processes that may affect distant tissues and organ systems. This understanding has led to increased interest in targeted probiotic supplementation as a means of supporting optimal microbial balance and promoting overall wellness through gut health optimization.

The concept of the gut-brain axis has been well-established in scientific literature, demonstrating clear communication pathways between the digestive system and central nervous system. Similarly, emerging research on the gut-spine axis suggests that digestive health may influence spinal comfort through related mechanisms involving inflammation, immune function, and neural communication pathways.

Factors that can disrupt healthy gut microbiome balance include antibiotic use, dietary choices, stress, environmental toxins, and aging processes. These disruptions may contribute to dysbiosis, a condition characterized by imbalanced bacterial populations that may compromise digestive function and potentially affect systemic health outcomes including inflammation regulation and immune function.

Targeted probiotic supplementation, such as that provided by BackBiome, aims to restore healthy microbial balance by introducing beneficial bacterial strains that may help compete with potentially harmful microorganisms while supporting optimal digestive function. The multi-strain approach used in BackBiome recognizes that different bacterial species contribute various benefits to overall gut health and systemic wellness.

The honey delivery matrix employed in BackBiome serves multiple functions within this probiotic wellness framework, acting as both a protective medium for sensitive bacterial strains and a prebiotic substrate that nourishes beneficial microorganisms. This comprehensive approach reflects current understanding of optimal probiotic supplementation strategies for maximum therapeutic potential.

Getting Started with BackBiome Supplementation

Beginning your BackBiome journey is straightforward and requires minimal preparation or lifestyle changes. The supplement is designed to integrate easily into existing daily routines while providing comprehensive support for digestive health and potential spinal wellness benefits through the emerging gut-spine axis connection. Most users find that establishing a consistent daily routine optimizes their results with probiotic supplementation.

Before starting BackBiome supplementation, individuals with serious health conditions, those taking medications, pregnant or breastfeeding women, and anyone with compromised immune systems should consult with their healthcare provider. While probiotic supplements are generally considered safe for healthy adults, professional guidance ensures that supplementation is appropriate for individual circumstances.

The ordering process for BackBiome is designed to be simple and secure, with all purchases made through the official website to ensure product authenticity and quality. Customers can choose from multiple package options based on their commitment level and budget, with larger packages offering enhanced value for users planning extended supplementation periods.

Upon receiving BackBiome, users should store the supplement according to package instructions to maintain optimal probiotic viability. The honey-based formulation provides natural preservation properties, but proper storage helps ensure maximum effectiveness throughout the product's shelf life. Most users begin with the recommended daily serving size and maintain consistency for optimal results.

New users should track their experiences during the initial weeks of supplementation, noting any changes in digestive comfort, energy levels, or spinal wellness as their gut microbiome adapts to the introduction of beneficial bacterial strains. This tracking helps users optimize their supplementation routine and identify the benefits they experience with BackBiome use.

About BackBiome

BackBiome represents a specialized approach to probiotic supplementation that focuses on the emerging connection between digestive health and spinal wellness. The company's mission centers on providing science-based nutritional support that addresses the growing understanding of how gut microbiome balance may influence comfort and wellbeing throughout the body, particularly in relation to spinal health.

The development of BackBiome's honey-based probiotic formulation reflects extensive research into optimal delivery methods for beneficial bacterial strains. By combining traditional knowledge about honey's therapeutic properties with modern understanding of probiotic science, BackBiome aims to provide enhanced effectiveness compared to conventional probiotic supplements that may not adequately protect bacterial viability during digestion.

BackBiome's commitment to quality extends throughout the manufacturing and distribution process, with all products manufactured in GMP-certified facilities and subjected to rigorous third-party testing for potency, purity, and safety. This comprehensive approach to quality assurance helps ensure that consumers receive consistent, effective products that meet the highest safety standards.

The company's focus on the gut-spine axis represents recognition of emerging scientific understanding about the interconnected nature of human physiology. Rather than addressing digestive health and spinal comfort as separate concerns, BackBiome's approach acknowledges that optimal wellness often requires comprehensive strategies that address underlying biological connections between different body systems.

Media Contact:

BackBiome
Andre Harrelson.

Website: https://getbackbiome.com/
Contact: order@getbackbiome.com
+1 (886) 647-6501
4711 34th St N, Suite 3, St. Petersburg, Florida 33714, USA.

References

  1. PMC/NIH. "Bifidobacterium treatment for chronic low back pain in patients with Modic changes: study protocol for a multicenter randomized placebo-controlled trial." September 24, 2025. https://pmc.ncbi.nlm.nih.gov/articles/PMC12462194/
  2. PMC/NIH. "The probiotic Bacillus subtilis BS50 decreases gastrointestinal symptoms in healthy adults: a randomized, double-blind, placebo-controlled trial." October 21, 2022. https://pmc.ncbi.nlm.nih.gov/articles/PMC9590435/
  3. PMC/NIH. "Effects of Bacillus subtilis var. natto products on symptoms caused by blood-flow insufficiency." January 20, 2015. Study showed improvements in circulation-related symptoms including low back pain relief. https://pmc.ncbi.nlm.nih.gov/articles/PMC4310345/
  4. Medscape. "Gut Microbiome Changes in Chronic Pain — Test and Treat?" June 11, 2025. https://www.medscape.com/viewarticle/gut-microbiome-changes-chronic-pain-test-and-treat-2025a1000fo1
  5. Frontiers in Microbiology. "Genetically predicted causal effects of gut microbiota on spinal pain." March 24, 2024. https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1357303/full

Disclaimer

Important Notice: The information provided in this document is for educational and informational purposes only and is not intended as medical advice. BackBiome is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease or medical condition.

The statements regarding BackBiome have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to replace professional medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider before starting any new dietary supplement, especially if you have pre-existing medical conditions, are taking medications, are pregnant or breastfeeding, or have a compromised immune system.

Individual results may vary. The consumer satisfaction percentages and user reports cited in this document are based on internal surveys and self-reported experiences, which are subjective and may not reflect the experience of all users. Scientific research referenced herein is provided for informational context and does not constitute an endorsement or guarantee of specific outcomes from BackBiome supplementation.

Affiliate Disclosure: This document may contain affiliate links. We may earn a commission if you purchase products through the links provided, at no additional cost to you. This disclosure is provided in accordance with the Federal Trade Commission's guidelines on endorsements and testimonials.

The research studies cited in the References section are independent scientific publications and do not specifically evaluate the BackBiome product. They are referenced to provide scientific context for the ingredients and mechanisms discussed. BackBiome is not claiming to replicate the results of these studies.

Attachment


BackBiome
Andre Harrelson.

Website: https://getbackbiome.com/
Contact: order@getbackbiome.com
+1 (886) 647-6501
4711 34th St N, Suite 3, St. Petersburg, Florida 33714, USA.